Antibacterial Activity Testing Propionibacterium acnes Combination of 70% Ethanol Extract of Starfruit Leaves (Averrhoa bilimbi L.) and Jarak Pagar Leaves (Jatropha curcas L.)

Tarisya Anilya Dwi Putri, Agnes Yuliana, Krismayadi Krismayadi

Abstract


Acne is an inflammation accompanied by blockage of oil gland ducts that gather and cause blackheads. The onset of acne can be caused by the bacterium Propionibacterium acnes. Flavonoid compounds and tannins contained in star fruit leaves and jatropha leaves can be used as antibacterials. Both extracts from the plant can be combined to achieve antibacterial effects that can be used as an alternative to acne treatment. The purpose of this study was to determine the antibacterial activity of star fruit leaf extract and jatropha leaf and determine the optimal concentration resulting from the antibacterial activity of the extract combination. The method used is experimental and antibacterial tests in vitro. The results of antibacterial tests on the combination of jatropha leaf extract and star fruit leaf extract against P. acnes had the most optimal average inhibitory zone of 9,642 mm with a ratio of 1:2 at a concentration of 10%.

Keywords


Averrhoa bilimbi L.; combination extract; Jatropha curcas L.; Propionibacterium acnes

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References


Afifi, R., Erlin, E., & Rachmawati, J. (2018). Uji Antibakteri Ekstrak Daun Belimbing Wuluh (Averrhoa bilimbi L) Terhadap Zona Hambat Bakteri Jerawat Propionibacterium acnes Secara In Vitro. Quagga: Jurnal Pendidikan Dan Biologi, 10(1), 10–17. https://doi.org/10.25134/quagga.v10i01.803

Amalia, A., Sari, I., & Nursanty, R. (2017). Aktivitas Antibakteri Ekstrak Etil Asetat Daun Sembung (Blumea balsamifera (L.) DC.) terhadap Pertumbuhan Bakteri Methicillin Resistant Staphylococcus aureus (MRSA). Jurnal UIN Ar-Raniry, 5(1), 387–391.

Andriani, M., Permana, I. D. G. M., & Widarta, I. W. R. (2019). Pengaruh Suhu dan Waktu Ekstraksi Daun Belimbing Wuluh (Averrhoa bilimbi L.) terhadap Aktivitas Antioksidan dengan Metode Ultrasonic Assisted Extraction (UAE). Jurnal Ilmu Dan Teknologi Pangan, 8(3), 330–340.

Aryantini, D., Sari, F., & Juleha. (2017). Uji Aktivitas Antibakteri Fraksi Aktif Terstandar Flavonoid Dari Daun Belimbing Wuluh (Averrhoa bilimbi L.). Jurnal Wiyata, 4(2), 143–150.

Asdika, R., Fitri, E. W., & Desiana. (2020). Perbandingan Efektivitas Klinis Topikal Niacinamide 4% dan Topikal Clindamycin 1% pada Acne Vulgaris Ringan-Sedang di Program Studi Pendidikan Dokter Fakultas Kedokteran Universitas Abulyatama. Jurnal Riset Dan Inovasi Pendidikan Perbandingan, 2(1), 50–57.

Febriani, P., Indah, D., Djamil, R., Taurhesia, S., Sari, K., Mayer, P., Dragendorff, P., Alkohol, A., & Liebermann-, P. (2022). Daya Hambat Bakteri Propionibacterium acnes Gel Kombinasi Ekstrak Kulit Buah Manggis (Garcinia mangostana L.) dan Ekstrak Sari Jeruk Bali (Citrus maxima Merr). Jurnal Ilmu Kesehatan, 16(1), 22–28.

Hasanah, N., & Novian, D. R. (2020). Daya Hambat Ekstrak Daun Belimbing Wuluh (Averrhoa bilimbi L) Terhadap Bakteri Penyebab Jerawat (Propionibacterium acnes). Poltek Tegal, 9(1), 46–53.

Hasim, H., Arifin, Y. Y., Andrianto, D., & Faridah, D. N. (2019). Ekstrak Etanol Daun Belimbing Wuluh (Averrhoa bilimbi) sebagai Antioksidan dan Antiinflamasi. Jurnal Aplikasi Teknologi Pangan, 8(3), 86–93. https://doi.org/10.17728/jatp.4201

Jayanti, P. D. M. (2021). Uji Aktivitas Antibakteri Fraksi Etanol dan N-heksan kulit Bawang Merah (Allium cepa L.) terhadap bakteri Propionibacterium acnes penyebab jerawat. In Stikes Bhakti Husada Mulia Madiun.

Juliansyah, R., & Paotonan, R. (2017). Uji Daya Hambat Sediaan Sabun Transparan Ekstrak Jarak Pagar (Jatropha curcas) Terhadap Pertumbuhan Bakteri Uji Propionibacterium acnes. Jurnal Mandala Pharmacon Indonesia, 3(2), 103–109. https://doi.org/10.35311/jmpi.v3i02.6

Nahor, E. M., Maramis, R. N., Dumanauw, J. M., Rintjap, D. S., & Andaki, K. A. M. (2022). Perbandingan Rendemen Ekstrak Tanaman Belimbing Wuluh (Averrhoa bilimbi L.) dengan Metode Maserasi. E-Prosiding Seminar Nasional, 01(02), 202–208.

Novaryatiin, S. (2016). Identifikasi Bakteri dan Resistensinya Terrhadap Antibiotik di Poli Gigi RSUD Dr. Doris Sylvanus Palangka Raya. Jurnal Surya Medika, 1(2), 17–25. https://doi.org/10.33084/jsm.v1i2.395

Puspita, A. (2021). Optimasi Sediaan Gel Antijerawat Ekstrak Daun Belimbing Wuluh (Averrhoa blimbi) dengan Gelling Agent Hpmc dan Humektan Propilen Glikol: Desain Faktorial. Universitas Sanata Dharma.

Rahmi, A., Cahyanto, T., Sujarwo, T., & Indri, R. (2015). Uji Aktivitas Antibakteri Ekstrak Daun Beluntas (Pluchea indica (L.) Less.) Terhadap Propionibacterium acnes Penyebab Jerawat. ISSN 1979-8911, 9(1), 141–161.

RI, K. K. (2017). Farmakope Herbal Indonesia Edisi II. In Kementrian Kesehatan RI. Kementrian Kesehatan RI. https://doi.org/10.1201/b12934-13

Saraswati, & Karina. (2016). Daya Antibakteri Ekstrak Etanol Daun Jarak Pagar (Jatropha curcas L.) Terhadap Pertumbuhan Enterococcus faecalis. In Journal of Chemical Information and Modeling (Vol. 53, Issue 9).

Winastri, N. L. A. P., Muliasari, H. M., & Hidayati, E. (2020). Aktivitas Antibakteri Air Perasan Dan Rebusan Daun Calincing (Oxalis corniculata L.) Terhadap Streptococcus mutans. Berita Biologi, 19(2). https://doi.org/10.14203/beritabiologi.v19i2.3786




DOI: https://doi.org/10.14421/biomedich.2024.132.591-594

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Biology, Medicine, & Natural Product Chemistry
ISSN 2089-6514 (paper) - ISSN 2540-9328 (online)
Published by Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity.

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