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Phytochemical Profile, Antioxidant Activity, and Brine Shrimp Lethality Test of Thyrsostachys siamensis (Siamese Bamboo) Leaf Extracts
Abstract
Cancer and oxidative-stress–related disorders continue to rise globally, driving interest in plant-based antioxidants with concurrent cytotoxic potential. This study aimed to characterize the phytochemical profile, antioxidant activity, and brine shrimp (Artemia salina) lethality of Thyrsostachys siamensis (Siamese bamboo) leaf extracts obtained with solvents of increasing polarity (n-hexane, chloroform, acetone, ethyl acetate, methanol, ethanol, and water). Ethanol appears as the most effective solvent for T. siamensis, combining a solid extraction yield (7.78%) with the richest phytochemical profile (positive for alkaloids, flavonoids, saponins, tannins, and phenolics). This broad chemical recovery corresponds to the strongest bioactivity, shown by its lowest IC50 (91.48 ± 0.12 µg/mL) and LC50 (80.78 ± 0.62 µg/mL). Acetone (6.42%) and ethyl acetate (5.11%) offer moderate yields and selective enrichment of semi-polar constituents, reflected in intermediate IC50 values (144–150 µg/mL) and LC50 values (273–350 µg/mL). In contrast, hexane despite providing the highest mass recovery (11.34%) contains mainly non-phenolic components and shows weak biological activity (IC50 200.52 ± 0.38 µg/mL, LC50 620.06 ± 0.76 µg/mL). Chloroform, with limited phytochemical content, yields the poorest performance (IC50 238.30 ± 1.56 µg/mL, LC50 926.40 ± 4.27 µg/mL).
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Abdelfatah, A. M., Fawzy, M., El-Khouly, M. E., & Eltaweil, A. S. (2021). Efficient adsorptive removal of tetracycline from aqueous solution using phytosynthesized nano-zero valent iron. Journal of Saudi Chemical Society, 25(12), 101365. https://doi.org/10.1016/j.jscs.2021.101365
Adeshina, I., Paray, B. A., Bhat, E. A., Sherzada, S., Fawole, O. O., Bawa, D. J., Cruz, T. P. D., & Tiamiyu, L. O. (2024). Dietary ? ?Mannanase Affects the Growth, Antioxidant, and Immunes Responses of African Catfish, Clarias gariepinus , and Its Challenge Against Aeromonas hydrophila Infection. Aquaculture Nutrition, 2024(1), 5263495. https://doi.org/10.1155/2024/5263495
Adu, J. K., Amengor, C. D. K., Kabiri, N., Orman, E., Patamia, S. A. G., & Okrah, B. K. (2019). Validation of a Simple and Robust Liebermann–Burchard Colorimetric Method for the Assay of Cholesterol in Selected Milk Products in Ghana. International Journal of Food Science, 2019, 1–7. https://doi.org/10.1155/2019/9045938
Ahmed, R. A., Jastaniah, S. D., Alaidaroos, B. A., Shafi, M. E., El-Haroun, E., Abd El-Aziz, Y. M., Abd El Megeed, O. H., AL-Qurashi, M. M., Bahshwan, S. M., & Munir, M. B. (2025). Effects of dietary Spirulina platensis supplementation on growth performance, whole body composition, antioxidant activity, histological alterations, and resistance to Vibrio parahaemolyticus in Pacific white shrimp, Litopenaeus vannamei. Aquaculture Reports, 40, 102606.
Álvarez-Alarcón, N., Osorio-Méndez, J. J., Ayala-Fajardo, A., Garzón-Méndez, W. F., & Garavito-Aguilar, Z. V. (2021). Zebrafish and Artemia salina in vivo evaluation of the recreational 25C-NBOMe drug demonstrates its high toxicity. Toxicology Reports, 8, 315–323. https://doi.org/10.1016/j.toxrep.2021.01.010
American Cancer Society. (2024). Global Cancer Facts & Figures, 5th edition. https://www.cancer.org/research/cancer-facts-statistics/global-cancer-facts-and-figures.html
Amin, A., & Park, S. (2025). Chemotaxonomy, an Efficient Tool for Medicinal Plant Identification: Current Trends and Limitations. Plants, 14(14), 2234. https://doi.org/10.3390/plants14142234
Andini, A., Nidianti, E., & Prayekti, E. (2020). Cytotoxicity Assay of Chitosan-Collagen Wound Dressing using Brine Shrimp Lethality Test Methods. Biomedika, 13(1), 9–14. https://doi.org/10.31001/biomedika.v13i1.680
Baliyan, S., Mukherjee, R., Priyadarshini, A., Vibhuti, A., Gupta, A., Pandey, R. P., & Chang, C.-M. (2022). Determination of antioxidants by DPPH radical scavenging activity and quantitative phytochemical analysis of Ficus religiosa. Molecules, 27(4), 1326.
Barbouchi, M., Benzidia, B., Elamrani, K., Sabiri, M., El Idrissi, M., & Choukrad, M. (2024). Phytochemical screening, quantitative analysis and antioxidant properties of crude extracts from stems, leaves, and flowers of three Ruta species. Kuwait Journal of Science, 51(4), 100287. https://doi.org/10.1016/j.kjs.2024.100287
Bray, F., Laversanne, M., Sung, H., Ferlay, J., Siegel, R. L., Soerjomataram, I., & Jemal, A. (2024). Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 74(3), 229–263. https://doi.org/10.3322/caac.21834
Cao, G., Yu, Y., Wang, H., Liu, J., Zhang, X., Yu, Y., Li, Z., Zhang, Y., & Yang, C. (2022). Effects of Oral Administration of Bamboo (Dendrocalamus membranaceus) Leaf Flavonoids on the Antioxidant Capacity, Caecal Microbiota, and Serum Metabolome of Gallus gallus domesticus. Frontiers in Nutrition, 9, 848532. https://doi.org/10.3389/fnut.2022.848532
Chaves Girão Neto, C. A., Richter, C., Medeiros Prasilde, I. C., Marques Canuto, K., Turini Da Cunha, M. E., Moerschbacher, B. M., Soares Rodrigues, T. H., & Ponte Rocha, M. V. (2025). Cymbopogon winterianus essential oil as an alternative source for producing terpenic esters with potential plant-protective antifungal activity using lipase immobilized on a lignin composite. Biocatalysis and Agricultural Biotechnology, 69, 103746. https://doi.org/10.1016/j.bcab.2025.103746
Džari?, T., Petrovi?, D., & Božovi?, M. (2025). Antioxidant Activity and Total Phenolic Content of Different Extracts from Rosa canina L Fruits. Natural Product Communications, 20(8), 1934578X251369590. https://doi.org/10.1177/1934578X251369590
Fatima, I., Akhtar, W., Bangash, N. K., Kanwal, S., Rauf, N., Malik, T. S., & Mahmood, T. (2022). Volatile profiling, elemental composition and biological activities of aerial parts of seven Poaceae species. Plant Biosystems-An International Journal Dealing with All Aspects of Plant Biology, 156(4), 908–925.
Fikroh, R. A., & Hidayah, M. A. (2025). Phytochemicals Compound and Antioxidant Activity of Tradescantia spathacea Sw. Leaf Extracts. Biology, Medicine, & Natural Product Chemistry, 14(1), 283–288.
Gondhowiardjo, S. A., Octavianus, S., & Maharani, P. (2021, February 17). INDONESIA NATIONAL ACTION PLAN for Cancer Control 2020 – 2024. Indico for IAEA Conferences (Indico). International Conference on Advances in Radiation Oncology #ICARO3, Indonesia. https://conferences.iaea.org/event/229/contributions/18619/?utm_source=chatgpt.com
Gondhowiardjo, S., Christina, N., Ganapati, N. P. D., Hawariy, S., Radityamurti, F., Jayalie, V. F., Octavianus, S., Prawira Putra, A., Sekarutami, S. M., Prajogi, G. B., Giselvania, A., Adham, M., Hamid, A. R. A. H., Widyastuti, E., Prabowo, Y., Aninditha, T., Purwoto, G., Aman, R. A., Siregar, T. P., … Agianda, F. (2021). Five-Year Cancer Epidemiology at the National Referral Hospital: Hospital-Based Cancer Registry Data in Indonesia. JCO Global Oncology, 7, 190–203. https://doi.org/10.1200/GO.20.00155
Góral, I., & Wojciechowski, K. (2020). Surface activity and foaming properties of saponin-rich plants extracts. Advances in Colloid and Interface Science, 279, 102145. https://doi.org/10.1016/j.cis.2020.102145
Gulcin, ?., & Alwasel, S. H. (2023). DPPH Radical Scavenging Assay. Processes, 11(8), 2248. https://doi.org/10.3390/pr11082248
Hernandez-Fuentes, G. A., Delgado-Enciso, O. G., Larios-Cedeño, E. G., Sánchez-Galindo, J. M., Ceballos-Magaña, S. G., Pineda-Urbina, K., Alcalá-Pérez, M. A., Magaña-Vergara, N. E., Delgado-Enciso, J., Díaz-Llerenas, U., Diaz-Martinez, J., Garza-Veloz, I., Martinez-Fierro, M. L., Rodriguez-Sanchez, I. P., & Delgado-Enciso, I. (2024). Comparative Analysis of Infusions and Ethanolic Extracts of Annona muricata Leaves from Colima, Mexico: Phytochemical Profile and Antioxidant Activity. Life, 14(12), 1702. https://doi.org/10.3390/life14121702
Hidayah, M. A., Tunjungsari, G. P., Fikroh, R. A., Mashadi, H., Handayani, T., & Nurohmah, B. A. (2022). Antihyperuricemia Potential in Ethanol Extract of Siamese Bamboo (Thyrsostachys siamensis) Leaves on Male White House Mice (Mus musculus L.). Walisongo Journal of Chemistry, 5(2), Article 2. https://doi.org/10.21580/wjc.v5i2.10666
Jameel, Q., Jameel, T., & Mohammed, N. (2025). Preventive and therapeutic effects of natural antioxidants against damage caused by X-rays. Bioactive Compounds in Health and Disease-Online ISSN: 2574-0334; Print ISSN: 2769-2426, 8(1), 11–30.
Jomova, K., Alomar, S. Y., Valko, R., Fresser, L., Nepovimova, E., Kuca, K., & Valko, M. (2025). Interplay of oxidative stress and antioxidant mechanisms in cancer development and progression. Archives of Toxicology, 1–47.
Kalauni, S. K., Bhattarai, G., & Khanal, L. N. (2024). Evaluation of Antioxidant, Toxicity, and Antidiabetic Activities of Young Sprouts of Hordeum vulgare, Triticum aestivum, and Zea mays. Journal of Institute of Science and Technology, 29(1), 75–84. https://doi.org/10.3126/jist.v29i1.63637
Kasemsukphaisan, S., & Maksup, S. (2022). Phytochemical Profiling, Antioxidant, and Antityrosinase Activities of Bamboo Leaves in Thailand. Applied Science and Engineering Progress. https://doi.org/10.14416/j.asep.2022.09.002
Konan, A. M. L., Golly, K. J., Kra, A. K. M., Adima, A. A., & Lohoues, E. E. C. (2022). Phytochemical screening and toxicity assessment of Imperata cylindrica (L.) P. Beauv.(Poaceae) raw extracts with brine shrimp (Artemia salina) lethality assay. Journal of Biosciences and Medicines, 10(8), 153–171.
Lazuardi, M., Suharjono, S., Chien, C.-H., He, J.-L., Lee, C.-W., Peng, C.-K., Sukmanadi, M., Sugihartuti, R., & Maslachah, L. (2022). Toxicity test of flavonoid compounds from the leaves of Dendrophthoe pentandra (L.) Miq. Using in vitro culture cell models. Veterinary World, 2896–2902. https://doi.org/10.14202/vetworld.2022.2896-2902
Lima-Pereira, Y., de Souza, E. M. O., dos Reis, D. S., Barcellos-Silva, I. G. C., Miki, K. S. L., Veiga-Júnior, V. F., & Teixeira-Costa, B. E. (2025). Current Perspectives on the Extraction, Isolation, and Identification of Fats and Fatty Acids Using Conventional and Green Methods. Separations, 12(6), 160. https://doi.org/10.3390/separations12060160
Lohvina, H., Sándor, M., & Wink, M. (2021). Effect of Ethanol Solvents on Total Phenolic Content and Antioxidant Properties of Seed Extracts of Fenugreek (Trigonella foenum-graecum L.) Varieties and Determination of Phenolic Composition by HPLC-ESI-MS. Diversity, 14(1), 7. https://doi.org/10.3390/d14010007
Maheshwaran, L., Nadarajah, L., Senadeera, S. P. N. N., Ranaweera, C. B., Chandana, A. K., & Pathirana, R. N. (2024). Phytochemical Testing Methodologies and Principles for Preliminary Screening/ Qualitative Testing. Asian Plant Research Journal, 12(5), 11–38. https://doi.org/10.9734/aprj/2024/v12i5267
Metrouh-Amir, H., Duarte, C. M. M., & Maiza, F. (2015). Solvent effect on total phenolic contents, antioxidant, and antibacterial activities of Matricaria pubescens. Industrial Crops and Products, 67(Copyright © 2024 American Chemical Society (ACS). All Rights Reserved.), 249–256. https://doi.org/10.1016/j.indcrop.2015.01.049
Mungwari, C. P., King’ondu, C. K., Sigauke, P., & Obadele, B. A. (2025). Conventional and modern techniques for bioactive compounds recovery from plants: Review. Scientific African, 27, e02509. https://doi.org/10.1016/j.sciaf.2024.e02509
Narzary, R., Wary, R. R., Basumatary, J., Kalita, P., Middha, S. K., Usha, T., & Goyal, A. K. (2025). Unveiling the nutritional and bioactive potential of bamboo (Bambusa tulda Roxb.) tea: A phytochemical and spectroscopic study. Advances in Bamboo Science, 10, 100132. https://doi.org/10.1016/j.bamboo.2025.100132
National Cancer Institute. (2025, May 7). Cancer Statistics (nciglobal,ncienterprise) [cgvArticle]. https://www.cancer.gov/about-cancer/understanding/statistics
Nerdy, N., Lestari, P., Sinaga, J. P., Ginting, S., Zebua, N. F., Mierza, V., & Bakri, T. K. (2021). Brine Shrimp (Artemia salina Leach.) Lethality Test of Ethanolic Extract from Green Betel (Piper betle Linn.) and Red Betel (Piper crocatum Ruiz and Pav.) through the Soxhletation Method for Cytotoxicity Test. Open Access Macedonian Journal of Medical Sciences, 9(A), 407–412. https://doi.org/10.3889/oamjms.2021.6171
Noreen, S., Tufail, T., Mubashar, H., Bader-Ul-Ain, H., Hassan, A., Zafar, A., Aja, P. M., & Atoki, A. V. (2025). Antioxidant activity and phytochemical analysis of different varieties of barley (Hordeum vulgare L.) available in Pakistan. Frontiers in Nutrition, 12, 1618457.
Nurcholis, W., Marliani, N., Asyhar, R., & Minarni, M. (2023). Optimized Solvents for the Maceration of Phenolic Antioxidants from Curcuma xanthorrhiza Rhizome using a Simplex Centroid Design. Journal of Pharmacy and Bioallied Sciences, 15(1), 35. https://doi.org/10.4103/jpbs.jpbs_185_23
Nurcholis, W., Weni, M., Fitria, R., Manek, K. R., & Habibie, B. Y. (2019). Toxicity test of roots, stems and leaves of Lemongrass (Cymbopogon nardus). Current Biochemistry, 6(2), 78–85.
Palos-Hernández, A., González-Paramás, A. M., & Santos-Buelga, C. (2024). Latest Advances in Green Extraction of Polyphenols from Plants, Foods and Food By-Products. Molecules, 30(1), 55. https://doi.org/10.3390/molecules30010055
Palos-Hernández, A., González-Paramás, A. M., & Santos-Buelga, C. (2025). Latest Advances in Green Extraction of Polyphenols from Plants, Foods and Food By-Products. Molecules, 30(1), 55. https://doi.org/10.3390/molecules30010055
Paray, B. A., Bhat, E. A., Adebayo, A. O., Fawole, F. J., & Adeshina, I. (2025). Chemoprotection and Immunostimulation of Alpha?Lipoic Acid Against Chlorpyrifos?Induced Toxicosis in Nile Tilapia, Oreochromis niloticus. Scientifica, 2025(1), 9985059. https://doi.org/10.1155/sci5/9985059
Prasticha, Y. D. (2024). Brine Shrimp Lethality Test (BSLT) of 96% Ethanol Extract of Ande-ande Lumut (Selaginella doederleineii) Leaves. Biospecies, 17(2), 1–6.
Raal, A., Meos, A., Hinrikus, T., Heinämäki, J., Rom?ne, E., Gudien?, V., Koshovyi, O., Kovaleva, A., Fursenco, C., & Chiru, T. (2020). Dragendorff’s reagent: Historical perspectives and current status of a versatile reagent introduced over 150 years ago at the University of Dorpat, Tartu, Estonia. Die Pharmazie-An International Journal of Pharmaceutical Sciences, 75(7), 299–306.
Ramli, S., Sukri, N. N. S., Zulkifli, N. A., Ariestanti, D. M., Choo, C. Y., Halim, H., Manshoor, N., & James, R. J. (2024). Antioxidant Activities and Protective Effects of Shorea macrophylla Leaf and Bark Extracts. Pharmaceutical Sciences and Research, 11(1), 4.
Ren, J., Li, Z., Li, X., Yang, L., Bu, Z., Wu, Y., Li, Y., Zhang, S., & Meng, X. (2025). Exploring the Mechanisms of the Antioxidants BHA, BHT, and TBHQ in Hepatotoxicity, Nephrotoxicity, and Neurotoxicity from the Perspective of Network Toxicology. Foods, 14(7), 1095.
Sasu, P., Attoh-Kotoku, V., Anim-Jnr, A. S., Osman, A., Adjei, O., Adjei-Mensah, B., Edinam Aku Akoli, D., Adjima Tankouano, R., Kwaku, M., & Obloni Kweitsu, D. (2023). Comparative nutritional evaluation of the leaves of selected plants from the Poaceae family (bamboos and grasses) for sustainable livestock production in Ghana. Frontiers in Sustainable Food Systems, 7, 1087197.
Shahidi, F., & Samarasinghe, A. (2025). How to assess antioxidant activity? Advances, limitations, and applications of in vitro, in vivo, and ex vivo approaches. Food Production, Processing and Nutrition, 7(1), 50. https://doi.org/10.1186/s43014-025-00326-z
Shen, H., Wang, Y., Shi, P., Li, H., Chen, Y., Hu, T., Yu, Y., Wang, J., Yang, F., Luo, H., & Yu, L. (2024). Effects of the Species and Growth Stage on the Antioxidant and Antifungal Capacities, Polyphenol Contents, and Volatile Profiles of Bamboo Leaves. Foods, 13(3), 480. https://doi.org/10.3390/foods13030480
Shourove, J. H., Kazi, A. R., Emon, F. U., & Islam, G. M. R. (2025). Solvent-dependent efficiency of conventional and ultrasound-assisted extraction methods for antioxidants from Khasia betel leaves. Discover Food, 5(1), 359. https://doi.org/10.1007/s44187-025-00646-6
Situmorang, P. C., Ilyas, S., Nugraha, S. E., Syahputra, R. A., & Nik Abd Rahman, N. M. A. (2024). Prospects of compounds of herbal plants as anticancer agents: A comprehensive review from molecular pathways. Frontiers in Pharmacology, 15, 1387866. https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1387866/full
Sorriento, D. (2024). Oxidative Stress and Inflammation in Cancer. Antioxidants, 13(11), 1403. https://doi.org/10.3390/antiox13111403
Sridhar, K., & Charles, A. L. (2019). In vitro antioxidant activity of Kyoho grape extracts in DPPH and ABTS assays: Estimation methods for EC50 using advanced statistical programs. Food Chemistry, 275, 41–49.
Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., & Bray, F. (2021). Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 71(3), 209–249.
Swami, S., Sharma, R., Rani, S., Pundir, R., & Yogi, R. (2024). Antimicrobial, Antioxidant and Phytochemical Properties of Weeds of Poaceae Family. J Food Chem Nanotechnol, 10(S1), S23–S33.
Tadee, P., Chansakaow, S., Tipduangta, P., Tadee, P., Khaodang, P., & Chukiatsiri, K. (2023). Essential oil pharmaceuticals for killing ectoparasites on dogs. Journal of Veterinary Science, 25(1). https://doi.org/10.4142/jvs.23189
Taviano, M. F., Arena, P., Davì, F., Cavò, E., Spadaro, V., Raimondo, F. M., Cacciola, F., Laganà Vinci, R., Mondello, L., & Miceli, N. (2024). Contribution of Phenolic Compounds to the Antioxidant Activity of Leaf and Flower Extracts of Sinapis pubescens L. subsp. Pubescens ( Brassicaceae ). Chemistry & Biodiversity, 21(5), e202400272. https://doi.org/10.1002/cbdv.202400272
Techamahasaranont, J., Ponpang-nga, P., & Sirijariyawat, A. (2025). Physical and Antioxidant Properties of Bamboo Shoot: Impact of Boiling on Purine Content and Antioxidant Activity. CURRENT APPLIED SCIENCE AND TECHNOLOGY, e0264212. https://doi.org/10.55003/cast.2025.264212
Tourabi, M., Faiz, K., Ezzouggari, R., Louasté, B., Merzouki, M., Dauelbait, M., Bourhia, M., Almaary, K. S., Siddique, F., Lyoussi, B., & Derwich, E. (2025). Optimization of extraction process and solvent polarities to enhance the recovery of phytochemical compounds, nutritional content, and biofunctional properties of Mentha longifolia L. extracts. Bioresources and Bioprocessing, 12(1), 24. https://doi.org/10.1186/s40643-025-00859-8
Tuhanioglu, A., & Ubeyitogullari, A. (2022). Extraction of High-Value Lipids and Phenolic Compounds from Sorghum Bran via a Sequential Supercritical Carbon Dioxide Approach. ACS Food Science & Technology, 2(12), 1879–1887. https://doi.org/10.1021/acsfoodscitech.2c00266
Valdés, N. V., & Martins, E. R. (2019). Toxicological effect of essential oils of plants against Artemia salina. Revista Brasileira de Plantas Medicinais, 21, 261–268.
Valentin Bashige Chiribagula, Amuri Salvius Bakari, Philippe Okusa Ndjolo, Byanga Joh Kahumba, & Jean-Baptiste Lumbu Simbi. (2020). Phytochemical screening and antioxidant activity of methanolic extracts of 53 antimalarial plants from Bagira in Eastern DR Congo. GSC Biological and Pharmaceutical Sciences, 12(2), 099–118. https://gsconlinepress.com/journals/gscbps/content/phytochemical-screening-and-antioxidant-activity-methanolic-extracts-53-antimalarial-plants
Vázquez-Torres, M., Rivera-Portalatín, N., & Cabrera-Asencio, I. (2025). Phytochemical Profiling, Bioactivity, and Insecticidal Effectiveness of Mammea americana L. Leaf Extracts Against Ferrisia sp. Plants, 14(1), 21. https://doi.org/10.3390/plants14010021
Waghulde, S., Kale, M. K., & Patil, VijayR. (2019). Brine Shrimp Lethality Assay of the Aqueous and Ethanolic Extracts of the Selected Species of Medicinal Plants. The 23rd International Electronic Conference on Synthetic Organic Chemistry, 47. https://doi.org/10.3390/ecsoc-23-06703
World Health Organization. (2024). World Cancer Day 2024. https://www.emro.who.int/media/news/world-cancer-day-2024.html?utm_source=chatgpt.com
Xiang, Z., Liu, L., Xu, Z., Kong, Q., Feng, S., Chen, T., Zhou, L., Yang, H., Xiao, Y., & Ding, C. (2024). Solvent Effects on the Phenolic Compounds and Antioxidant Activity Associated with Camellia polyodonta Flower Extracts. ACS Omega, 9(25), 27192–27203. https://doi.org/10.1021/acsomega.4c01321
Yoo, O.-K., & Keum, Y.-S. (2019). 4’-O-?-D-Glucosyl-5-O-Methylvisamminol Attenuates Pro-Inflammatory Responses and Protects against Oxidative Damages. Biomolecules & Therapeutics, 27(Copyright © 2024 U.S. National Library of Medicine.), 381–385. https://doi.org/10.4062/biomolther.2018.232
DOI: https://doi.org/10.14421/biomedich.2026.151.379-389
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