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PKP Metadata Items |
Metadata for this Document |
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| 1. |
Title |
Title of document |
Physicochemical, Antimicrobial, Lethality and In Vitro Antioxidant Profiles of Johnu Tisane: A Coffee (Coffea Arabica) Leaf Decoction Formula |
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| 2. |
Creator |
Author's name, affiliation, country |
Anthony Cemaluk Chinedum Egbuonu; Michael Okpara University of Agriculture Umudike; Nigeria |
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Creator |
Author's name, affiliation, country |
Prince Ogochukwu Alaebo; Michael Okpara University of Agriculture Umudike; Nigeria |
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| 2. |
Creator |
Author's name, affiliation, country |
Udumma Nsofor Onuoha; Michael Okpara University of Agriculture Umudike; Nigeria |
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| 2. |
Creator |
Author's name, affiliation, country |
Chinomso Juliet Njoku; Michael Okpara University of Agriculture Umudike; Nigeria |
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| 2. |
Creator |
Author's name, affiliation, country |
Chiemeziem Adanma Obike; Michael Okpara University of Agriculture Umudike; Nigeria |
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| 2. |
Creator |
Author's name, affiliation, country |
Susan Ogechi Nlemadim; Michael Okpara University of Agriculture Umudike; Nigeria |
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| 2. |
Creator |
Author's name, affiliation, country |
Blessing Ifeoma Chukwu; Michael Okpara University of Agriculture Umudike; Nigeria |
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| 2. |
Creator |
Author's name, affiliation, country |
Sopuruchi Mary-Augusta Iwejuo; Michael Okpara University of Agriculture Umudike; Nigeria |
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| 2. |
Creator |
Author's name, affiliation, country |
Onyedikachi Glory Amaechi; Michael Okpara University of Agriculture Umudike; Nigeria |
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| 2. |
Creator |
Author's name, affiliation, country |
Victor Ifechukwu Obiefuna; Michael Okpara University of Agriculture Umudike; Nigeria |
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| 2. |
Creator |
Author's name, affiliation, country |
Bessing Nmesomachi Onuoha; Michael Okpara University of Agriculture Umudike; Nigeria |
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| 2. |
Creator |
Author's name, affiliation, country |
DivineTreasure Nzubechukwu Okoli; Michael Okpara University of Agriculture Umudike; Nigeria |
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| 2. |
Creator |
Author's name, affiliation, country |
Precious Chinonso Nwokeoma; Michael Okpara University of Agriculture Umudike; Nigeria |
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| 2. |
Creator |
Author's name, affiliation, country |
Chukwubuikem Eze; Michael Okpara University of Agriculture Umudike; Nigeria |
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| 3. |
Subject |
Discipline(s) |
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| 3. |
Subject |
Keyword(s) |
In-vivo anti-oxidative outcomes and roles; Johnu tisane; Requisite physicochemical mix; Requisite anti-oxidant capacity; Rich phyto-constituents-related diverse pharmacologic activities |
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| 4. |
Description |
Abstract |
Coffee leaves-based tea has relevance in ethno-medications due to its rich phyto-constituents-related diverse pharmacologic activities. Jonhu tisane, a typical Coffea arabica leaf decoction has no supporting scientific basis amidst reported location, processing and specie-related variations. This investigated physicochemical, antimicrobial, lethality and in-vitro antioxidant profiles of Johnu tisane by acceptable methods. Results recorded moisture (92.26 %), ash (0.65 %), unsaponified matter (1.46 mg/100 g), free fatty acid (0.56 mgKOH/g), acid value (1.12 mgKOH/g), potential hydrogen (6.85), lethal concentration (1000 ppm) and concentration-dependent antimicrobial activity. Anti-oxidation results revealed total antioxidant capacity, ferric reducing antioxidant power, nitric oxide, hydrogen peroxide and 2, 2-diphynyl-1-picrylhydrazyl scavenging activities increased concentration-dependently compared to standard. Thus, Johnu tisane demonstrated low minerals and keeping quality; requisite physicochemical mix for consumption and bioactivity; high safety margin; antimicrobial potency; and requisite anti-oxidation capacity for in-vivo antioxidant role. These provided scientific support for its ethno-medicinal uses. They underscored the need to elucidate its pharmacologically active compounds; mechanistic roles in animal models; and the impact of ash to moisture mix variation on potential hydrogen, microbial and antimicrobial activities in relation to shelf life, bioactivity and in vivo anti-oxidative roles for novel insights on preserving sample quality, safety, bioactivity and in-vivo anti-oxidative outcomes. |
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| 5. |
Publisher |
Organizing agency, location |
Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity |
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| 6. |
Contributor |
Sponsor(s) |
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| 7. |
Date |
(YYYY-MM-DD) |
2024-05-15
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| 8. |
Type |
Status & genre |
Peer-reviewed Article |
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| 8. |
Type |
Type |
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| 9. |
Format |
File format |
PDF |
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| 10. |
Identifier |
Uniform Resource Identifier |
https://sciencebiology.org/index.php/BIOMEDICH/article/view/462 |
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| 10. |
Identifier |
Digital Object Identifier (DOI) |
https://doi.org/10.14421/biomedich.2024.131.99-107 |
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| 11. |
Source |
Title; vol., no. (year) |
Biology, Medicine, & Natural Product Chemistry; Vol 13, No 1 (2024) |
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| 12. |
Language |
English=en |
en |
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| 13. |
Relation |
Supp. Files |
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| 14. |
Coverage |
Geo-spatial location, chronological period, research sample (gender, age, etc.) |
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| 15. |
Rights |
Copyright and permissions |
Copyright (c) 2024 Anthony Cemaluk Chinedum Egbuonu, Prince Ogochukwu Alaebo, Udumma Nsofor Onuoha, Chinomso Juliet Njoku, Chiemeziem Adanma Obike, Susan Ogechi Nlemadim, Blessing Ifeoma Chukwu, Sopuruchi Mary-Augusta Iwejuo, Onyedikachi Glory Amaechi, Victor Ifechukwu Obiefuna, Bessing Nmesomachi Onuoha, DivineTreasure Nzubechukwu Okoli, Precious Chinonso Nwokeoma, Chukwubuikem Eze
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