Antioxidant Activity Test of Bride's Tears (Antigonon leptopus) Leaves Using the DPPH Method

Nailil Wafiq Azizah, Majidah Ramadan, Faisal Faisal, Devana Rahma Aldina, Ramadina Novia Putri, Nur Laila Anggraini, Sabilatul Mufarrohah, Satria Gemilang, Firadika Fitriansyah, Hosiyah Hosiyah, Nuvia Harini Wulan Suci, Nihlatus Sofiya, Terra Januarista, Ramizard Rafsanjani

Abstract


Bridal tear leaves can be used to treat various health and beauty problems because they contain various active compounds, such as flavonoids, saponins, and tannins. These compounds have antioxidant, anti-inflammatory, and antibacterial properties. This flower contains antioxidants that can help protect the skin from damage caused by free radicals. This research aims to see the effectiveness of antioxidants from bridal tear leaves. The research method involves leaf extraction using 96% ethanol and testing antioxidant activity using the DPPH method. The research results showed that the extract sample from bride's tear leaves was (IC50 – 69.7146 ug/mL). This shows that the bride's tear leaf extract is quite strong in inhibiting free radical reactions.


Keywords


Antioxidant, Etanol Extract, DPPH.

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References


Budiyanto, M. S. A. (2015). Potensi Antioksidan, Inhibitor Tirosinase, dan Nilai Toksisitas dari Beberapa Spesies Tanaman Mangrove di Indonesia.Cavalcante GM, da Silva Cabral AE, Silva CC. 2018. Aktivitas Leishmanicide Flavonoid Alami dan Sintetis: Tinjauan Mini. Cetakan J. Pharm. medis. Sains. 2018; 7 :25–34.

Bujang, A. (2014). Changes on Amino Acid Content In Soybeans, Garbanzo beans and Groundnut During Pretreatment and Tempe Making, Sain Malaysian 43 (4): 551 - 557

Departemen Kesehatan Republik Indonesia. (2017). Farmakope Hebal Indonesia Edisi II. In Farmakope Herbal Indonesia.Juniarti et al.. Kandungan Senyawa Kimia, Uji Toksisitas (Brine Shrimp Lethality Test) dan antioksidan (1,1-diphenyl-2-pikrilhydrazy dari Ekstrak Daun Saga (Abrus precatorius L.). Makara, Sains. (2009) 13(1) 50-54. Tersedia dari: doi:https://doi.org/10.7454/mss.v1311.378.

Kurniawati, I., and Maftuch, H. A. (2016). Penentuan pelarut dan lama ekstraksi terbaik pada teknik maserasi Gracilaria sp. serta pengaruhnya terhadap kadar air dan rendemen. Jurnal Ilmu Perikanan. 2016. 7(2), 72-77.

Meidita, B. (2023). Teknik Budidaya Tanaman Air Mata Pengantin (Antigonon leptopus) Secara Generatif Dalam Mendukung Ketersediaan Pakan Lebah Kelulut (Trigona Spp.). UNIVERSITAS LAMBUNG MANGKURAT.

Meigaria, Komang Mirah, I Wayan Mudianta, and Ni Wayan Martiningsih. (2016). Skrining Fitokimia Dan Uji Aktivitas Antioksidan Ekstrak Aseton Daun Kelor (Moringa Oleifera). Jurnal Wahana Matematika dan Sains 10(2): 1–11.

Miksusanti, Elvita dan Hotdelina. S. (2012). Aktivitas Antioksidan dan Sifat Kestabilan Warna Campuran Ekstrak Etil Asetat Kulit Buah Manggis (Garcinia mangostana L.) dan Kayu Secang (Caesalpinia sappan L.). Junal Penelitian Sains. Universitas Sriwijaya, Sumatra Utara.

Pratimasari, D. (2009). Uji Aktivitas Penangkap Radikal Buah Carica papaya L. Dengan Metode DPPH dan Penetapan Kadar Fenolik Serta Flavonoid Totalnya, Fakultas Farmasi Universitas Muhammadiyah Surakarta. Surakarta.

Rahman, Arif, Abd Malik, and Aktsar Roskiana Ahmad. (2016). Skrining Fitokimia Dan Uji Aktivitas Antioksidan Ekstrak Etanolik Buah Buni (Antidesma Bunius (L.) Spreng). Jurnal Fitofarmaka Indonesia 3(2): 159–63.

Sepriyani, H., Devitria, R., Surya, A., & Sari, S. (2020). Aktivitas Antioksidan Ekstrak Metanol Daun Pepaya (Carica papaya L) Dengan Metode DPPH. Jurnal Penelitian Farmasi Indonesia, 9(1), DPPH. 10,863-867.

Simanjuntak, Kristina. (2012). Peran Antioksidan Flavonoid Dalam Meningkatkan Kesehatan. FK UPN Veteran Jakarta 3.

Suhaling, S. (2010). Uji Aktivitas Antioksidan Ekstrak Metanol Kacang Merah (Phaseolus vulgaris L.) dengan Metode DPPH. Skripsi. Universitas Islam Alauddin. Makasar.

Suryowinoto. S.M. (1997). Flora Eksotika, Tanaman Hias Berbunga. Penerbit Kanisius, Yogyakarta.

WHO. 2016. Media Centre Diabetes Mellitus. Retrieved Juni 03, 2024.

Zhao L., Yuan X., Wang J., Feng Y., Ji F., Li Z., Bian J. (2019). Tinjauan tentang flavon yang menargetkan protein kinase serin/treonin untuk obat antikanker potensial. Obat Bioorganik. kimia; 27 :677–685.




DOI: https://doi.org/10.14421/biomedich.2025.142.777-781

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Copyright (c) 2025 Nailil Wafiq Azizah, Majida Ramadhan*, Faisal, Devana Rahma Aldina, Ramadina Novia Putri, Nur Laila Anggraini, Sabilatul Mufarrohah, Satria Gemilang, Firadika Fitriansyah, Hosiyah, Nuvia Harini Wulan Suci, Nihlatus Sofiya, Terra Januarista, Ramizard Rafsa



Biology, Medicine, & Natural Product Chemistry
ISSN 2089-6514 (paper) - ISSN 2540-9328 (online)
Published by Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity.

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