Ethnobotanical Survey of Plants Used in The Management of Peptic Ulcer Diseases in Wukari Metropolis

Akpevwoghene Agbatutu, Efosa A. Ogie-Odia, Mary Oromioshemime Ifedele, Funmilola Modinat Abdulrasaq, Daniel Eseigbe, Francis Nosakhare Imade

Abstract


Peptic ulcer diseases (PUD) are sores formed in soft tissues present in the lining of the digestive tract as a result of excessive stomach acid or inability of the alimentary tract or stomach to protect itself. The increasing surge for plant based drugs in the management of PUD has increased scientific investigation of herbs and recipes from traditional medicinal practitioners (TMP) to ascertain their efficacy through pharmacological studies. Ethnobotanical survey of plants and recipes from TMP used in the management of PUD in Wukari metropolis, Taraba State, Northeastern Nigeria were documented. A total of twenty (20) TMP located in ten (10) different area of the town were interviewed using a semi structured questioner. Twenty-four (24) plant species from twenty (20) different families and sixteen (16) recipes were documented from the survey. It was observed that plant leaves were mostly used while C. longa (Zingberaceae), M. paradisiaca (Musaceae) had the highest frequency of occurrence in recipes formulation. Therefore, due to the proven efficacy of these herbal recipes as reported from correspondents, there is need for proper documentation, conservation, cultivation and use of these medicinal plants in the management of PUD to avoid them being endangered or going into extinction.

Keywords


Peptic ulcer; Wukari; Plant; Taraba

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Ajibola ES, Adeleye OE, Okediran BS and Rahman SA (2010). Effect of Intragastric Administration of Crude Aqueous Leaf Extract Of Anacardium occidentale on Gastric Acid Secretion in Rats. Nig. J. Physiol. Sci. 25. 59 – 62.

Akinwumi IA and Sonibare MA (2019). Use of medicinal plants for the treatment of gastric ulcer in some parts of Southwestern Nigeria. African Journal of Pharmacy and Pharmacology Vol. 13(15), pp. 223-235

Alebiosu CO, Ugwa OM, Ugwah-Oguejiofor CJ and Njan AA (2012). Ethnobotanical studies of medicinal plants used in the management of peptic ulcer disease in Sokoto State, North Western Nigeria. International Research Journal of Pharmacy and Pharmacology, 29(9): 225-230.

Amadi EN, Njoku OO, Okereke CN, Ndubuisi JL and Oguoma O (2014). Pharmachological Use of Ocimum gratissimum In Peptic Ulcer Diseases (Pud) Treatment. International Journal of Engineering & Science Research 4(6): 450-455.

Arciniegas A, Perez-Castorena, AL, Antonio, N, Kita, Y and Romo de Vivar A (2016). Antihyperglycemic, antioxidant and anti-inflammatory activities of extracts and metabolites from sida acuta and sida rhombifolia quim nova vol (10) pp 1-6.

Beverly CD and Sudarsanam G (2011). Ethnomedicinal plant knowledge and practice of people of Javadhu hills in Tamilnadu. Asian Pacific Journal of Tropical Biomedicine 1(1):79-81.

Burkill HM (1995). The Useful Plants of West Tropical Africa. 2nd Edition, Volume 1, Families A–D. Royal Botanic Gardens, Kew, Richmond, United Kingdom. pp. 21-25.

Chan KL and Leung, WK (2002). Peptic-ulcer disease Lancet 360: 933–41.

Dashputre NL and Naikwade NS (2011). Evaluation of Anti-Ulcer Activity of Methanolic Extract of Abutilon indicum Linn Leaves in Experimental Rats. International Journal of Pharmaceutical Sciences and Drug Research; 3(2): 97-100.

Dike IP, Obembe OO and Adebiyi FE (2012). Ethnobotanical survey for potential anti-malarial plants in south Western Nigeria. Journal of Ethnopharmacology, 144(3): 618-26.

Franco TG and Richter JE (1998). Proton pump inhibitors for gastric accelerated disease. Cleave. Clin. J. Med. 65: 27-34.

Gulmez SE, Holm A, Frederiksen H, Jensen TG and Pedersen C (2007). Use of proton pump inhibitors and the risk of community-acquired pneumonia: A Population-Based Case-Control Study. Arch. Intern. Med. 167: 950-955.

Gupta A, Surabhi M and Rajendra S (2015). Evaluation of antimicrobial activity of curcuma longa rhizome extract against Staphylococcus aureus. Biotechnol Rep. 73: 1-5.

Hooi JKY, Lai, WY, Ng WK, Suen MMY, Underwood FE, Tanyingoh D, Malfertheiner P, Graham DY, Wong VWS and Wu JCY (2017). Global prevalence of Helicobacter pylori infection: Systematic review and meta-analysis. Gastroenterology, 153, 420–429.

Iqbal Z, Sshehzad K, Nawaz S and Zahid M (2018). antimicrobial activity of essential oil of allium cepa world Journl of Pharmaceutical Research 7(2): 575-580.

Kuna L, Jakab J, Smolic R, Raguz-Lucic N, Vcev A and Smolic M (2019). Peptic Ulcer Disease: A Brief Review of Conventional Therapy and Herbal Treatment Options J. Clin. Med. 8: 179: 1-19.

Lanas A and Chan, FKL (2017). Peptic ulcer disease. Lancet, 390: 613–624.

Lanas A, García-Rodríguez LA, Polo-Tomás M, Ponce M, Quintero E, Perez-Aisa MA, Gisbert JP, Bujanda L, Castro M, Muñoz M et al. (2011). The changing face of hospitalisation due to gastrointestinal bleeding and perforation. Aliment. Pharmacol. Ther., 33: 585–591.

Malfertheiner P, Chan FKL. and McColl, KEL (2009). Peptic ulcer disease. The Lancet. 347: 1449-1461.

National Bureau of Statistics (NBS). (2006) Population Census. Available at http://www.nigerianstat.gov.ng. Accessed 15 April 2020.

Neelima N, Sudhakar M, Mrityunjaya B, Patil BVS and. Lakshmi (2012). Anti-ulcer Activity and HPTLC Analysis of Mangifera indica L. Leaves Int. J. Pharm. Phytopharmacol. Res. 1(4): 146-155.

Nihar RK, Shreechandan P, Priyadarshini P and Sampad SS (2017). Herbal Drugs in Treatment of Peptic Ulcer, J. Bio. Innov. 6 (3): 499-

Okewumi TA and oyeyemi AW (2012). Gastro-protective activity of aqueous Carica papaya seed extract on ethanol induced gastric ulcer in male rats. African Journal of Biotechnology, 11(34): 8612-8615.

Onwurah N, Ifeanyi GE and Aruh AO (2013). Antiulcer Properties Of Aqueous Extract Of Talinum triangulare Leaves In Experimentally Induced Gastric Ulceration In Mice. Asian J. Pharm. Biol. Res., 3(1): 4-7.

Oyatayo KT, John BA, Ademola JS, Abuh OP and Ndabula C (2017). Farmers perception and local agricultural adaptation practices to climate change in Wukari town, Wukari LGA Yaraba state Nigeria Journal of the General Studies Unit, Federal University Wukari. p28

Prabha P, Karpagam T, Varalakshmi B, Chandra S and Packiavathy A (2011). Indigenous anti-ulcer activity of Musa sapientum on peptic ulcer. Phcog Res 3: 232-8.

Rao M, Ahmad BA, Khamsah SM and Thant Z (2016). Antiulcer Activity of Musa paradisiaca (banana) Tepal And Skin Extracts In Ulcer Induced Albino Mice. Malaysian Journal of Analytical Sciences, Vol 20 No 5: 1203 – 1216.

Reilly JP (1999). Safety profile of the proton pump inhibitors AM. J. Health. Syst. Pharm. 56(23): S11-S17.

Roberts S (2003). In: Burger’s Medicinal Chemistry and Drug Discovery, 6th edn. Abraham DJ. editor. New Jersey: John Wiley. Pp.86-121.

Roy SD, Chakraborty J, Shil D, Das S and Begum N (2013). Herbs used in peptic ulcer: A review. Int. J. Pharm. Res. Allied Sci. 2:9-23.

Sarkar M, Hennessy S and Yang, YX (2008). Proton-pump inhibitor use and the risk for community-acquired pneumonia. Ann. Intern, Med. 149: 391-398.

Sen S, Chakraborty R, De B and Mazumder J (2009). Plants and phytochemicals for peptic ulcer: An overview. Pharmacogn. Rev.; 3: 270.

Sonnenberg A (2013).Historic changes of helicobacter pylori-associated diseases. Aliment. Pharmacol. Ther., 38, 329–342.

Subramanian S, Kumor DS, Aruiselvan P, Senthilkumar GP and Rao M (2007). Evaluation of antiulcerogenic potential of Aloe vera leaf gel extract studied in experimental rats. Journal of Pharmacology and Toxicology 2(1):85-97.

Wu Y and Fassihi R (2005). Stability of metronidazole, tetracycline HCl and famotidine alone and in combination. Int. J. Pharm. 290: 1-13.




DOI: https://doi.org/10.14421/biomedich.2022.112.137-143

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Copyright (c) 2022 Akpevwoghene Agbatutu, Francis Nosakhare Imade, Efosa A. Ogie-Odia, Mary Oromioshemime Ifedele, Funmilola Modinat Abdulrasaq, Daniel Eseigbe



Biology, Medicine, & Natural Product Chemistry
ISSN 2089-6514 (paper) - ISSN 2540-9328 (online)
Published by Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity.

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