Hibiscus rosa-sinensis L. (red Hibiscus) Tea, Can It Be Used as A Home-Remedy to Control Diabetes and Hypercholesterolemia?

Subhashinie Sanadheera, Deepanjana Subasinghe, Melissa Nethmi Solangaarachchi, Manju Suraweera, Noshara Yushanthi Suraweera, Nadeesha Tharangika


According to traditional medicine, Hibiscus is used to treat hypertension, heart diseases and many other ailments. Commercially available Hibiscus tea is prepared with H. sabdariffa and is expensive. H. rosasinensis is the common variety which is abundant in tropical home-gardens, however the scientific data are lacking on the effects. The present review focuses on the available scientific data on the effects of H. rosasinensis on controlling diabetes and hypercholesterolemia. The endeavour was to identify whether H. rosasinensis flower petals as a ‘tea’ is effective for diabetic and hypercholesterolemic patients. Medical databases such as MEDLINE, BMC, BMJ, research gate, Mendelay literature search database, Google scholar and the general engine Google were searched from November 2018 to April 2019. Search was carried out using keywords such as “Hibiscus rosasinensis”, “antidiabetic effects”, “antihyperlipidemic effects”, “toxic effects”, “anti-inflammatory effects”, “phytochemicals in Hibiscus” etc. Data were critically analyzed to assess whether the effective doses of the research studies on a par with the doses present in H. rosasinensis teas. We found thirty-nine journal articles fulfilled the criteria. The data were categorized and extracted on uses of H. rosasinensis, anti-diabetic effects, anti-inflammatory effects, anti-hypercholesterolemic effects and its phytochemicals. The review revealed that the dose of H. rosasinensis petals present in a home-made Hibiscus tea is theoretically sufficient to elicit anti-hyperglycemic and anti-hyperlipidemic effects. Home-made Hibiscus tea is effective in controlling diabetes and hypercholesterolemia without causing acute toxicity.


Hibiscus rosasinensis; Hibiscus sabdariffa; diabetes; hypercholesterolemia

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Afiune, L. A. F., Leal-Silva, T., Sinzato, Y. K., Moraes-Souza, R. Q., Soares, T. S., Campos, K. E., … Volpato, G. T. (2017). Beneficial effects of Hibiscus rosa-sinensis L. flower aqueous extract in pregnant rats with diabetes. PLoS ONE. https://doi.org/10.1371/journal.pone.0179785

Al-snafi, A. E. (2018). Chemical constituents and pharmacological activities of Gossypium herbaceum and Gossypium hirsutum-A review Chemical constituents and pharmacological activities of Gossypium herbaceum and Gossypium hirsutum - A review Prof Dr Ali Esmail Al-Snafi, (May).

Ali, Ö. (2010). Cytotoxicity of Hibiscus rosa-sinensis flower extract. Caryologia, 63(2), 157–161. https://doi.org/10.1080/00087114.2010.10589721 Ayurvedic Medicinal Plants of Sri Lanka. (n.d.).

Bhaskar, A., & Vidhya, V. G. (2012). Hypoglycemic and hypolipidemic activity of Hibiscus rosa sinensis Linn on streptozotocin-induced diabetic rats. International Journal of Diabetes in Developing Countries. https://doi.org/10.1007/s13410-012-0096-9

Birari, R. B., Jalapure, S. S., Changrani, S. R., Shid, S. L., Tote, M. V, Habade, B. M., … Thane, A. D. (2009). Pharmacologyonline, 3, 737–747. Retrieved from https://pharmacologyonline.silae.it/files/archives/2009/vol3/080.Birari.pdf

Donath, M. Y., & Shoelson, S. E. (2011). Type 2 diabetes as an inflammatory disease. Nature Reviews Immunology. https://doi.org/10.1038/nri2925

Ekor, M., & Pistelli, L. (2013). Frontiers The growing use of herbal medicines issues relating to adverse reactions and challenges in monitoring safety Pharmacology. Front Pharmacol, 177. https://doi.org/https://dx.doi.org/10.3389%2Ffphar.2013.00177

Goto, T., Takahashi, N., Hirai, S., & Kawada, T. (2010). Various Terpenoids Derived from Herbal and Dietary Plants Function as PPAR Modulators and Regulate Carbohydrate and Lipid Metabolism. PPAR Research, 2010, 1–9. https://doi.org/10.1155/2010/483958

Haji Faraji, M., & Haji Tarkhani, A. H. (1999). The effect of sour tea (Hibiscus sabdariffa) on essential hypertension. Journal of Ethnopharmacology. https://doi.org/10.1016/S0378-8741(98)00157-3

Hara, Y., & Honda, M. (1990). The Inhibition of a-Amylase by Tea Polyphenols control obesity or diabetes by diminishing the absorption of glucose decomposedfrom starch obtained ECg ) were 2 times more inhibitory than pyro- catechins ( GCg and EGCg ) respective-, 54(8), 1939–1945.

Harrison, A. P., Cooper, R. G., Suliman, M. A., & Alalami, U. (2009). The efficacy of karkadeh tea in controlling post-prandial blood glucose levels. American Journal of Pharmacology and Toxicology, 4(4), 151–157. https://doi.org/10.3844/ajptsp.2009.151.157

Jadhav et al. (2009). Traditional medicinal uses of Hibiscus rosa-sinensis. Journal of Pharmacy Research.

Johnston, J. J. (2005). Evaluation of Cocoa- and Coffee-Derived Methylxanthines as Toxicants for the Control of Pest Coyotes. Journal of Agricultural and Food Chemistry, 53(10), 4069–4075. https://doi.org/10.1021/jf050166p

Li, Y., Kim, J., Li, J., Liu, F., Liu, X., Himmeldirk, K., … Chen, X. (2005). Natural anti-diabetic compound 1,2,3,4,6-penta-O-galloyl-d-glucopyranose binds to insulin receptor and activates insulin-mediated glucose transport signaling pathway. Biochemical and Biophysical Research Communications, 336(2), 430–437. https://doi.org/10.1016/j.bbrc.2005.08.103

Linn, E., Gaur, K., Kori, M. L., & Nema, R. K. (2009). Investigation of Immunomodulatory Potential of Hydro-Alcoholic Extracts of Euphorbia neriifolia Linn. and Hibiscus rosa sinensis Linn., 2(1), 61–65.

Mak, Y. W., Chuah, L. O., Ahmad, R., & Bhat, R. (2013). Antioxidant and antibacterial activities of hibiscus (Hibiscus rosa-sinensis L.) and Cassia (Senna bicapsularis L.) flower extracts. Journal of King Saud University - Science, 25(4), 275–282. https://doi.org/10.1016/j.jksus.2012.12.003

McKay, D. L., Chen, C.-Y. O., Saltzman, E., & Blumberg, J. B. (2010). Hibiscus Sabdariffa L. Tea (Tisane) Lowers Blood Pressure in Prehypertensive and Mildly Hypertensive Adults. The Journal of Nutrition, 140(2), 298–303. https://doi.org/10.3945/jn.109.115097

Meena, A. K., Jain, A., Pandey, K., & Singh, R. K. (2014). Acute toxicity and genotoxic activity of Hibiscus rosa sinensis flower extract. American Journal of Phytomedicine and Clinical Therapeutics, 2(4), 524–529.

Mishra, M. (2009). an Analytical Review of Plants for Anti Diabetic Activity With Their Phytoconstituent & Mechanism of Action. International Journal of Pharmaceutical Sciences and Research, 1(1), 29–46.

Mohammed J, K., . A., Amber, V., Manju, S., & Deependra, S. (2011). Acute and Chronic Effect of Hibiscus rosa sinensis Flower Extract on Anxiety Induced Exploratory and Locomotor Activity in Mice. Journal of Plant Sciences, 6(2), 102–107. https://doi.org/10.3923/jps.2011.102.107

Mukherjee, P. K. (2002). Quality control of herbal drugs: an approach to evaluation of botanicals. Business Horizons, 113–119.

Nakamura, Y., Hidaka, M., Masaki, H., Seto, H., & Uozumr, T. (1990). Major anthocyanin of the flowers of hibiscus (Hibiscus rosa-sinensis L.). Agricultural and Biological Chemistry, 54(12), 3345–3346. https://doi.org/10.1080/00021369.1990.10870458

Ojeda, D., Jiménez-Ferrer, E., Zamilpa, A., Herrera-Arellano, A., Tortoriello, J., & Alvarez, L. (2010). Inhibition of angiotensin convertin enzyme (ACE) activity by the anthocyanins delphinidin- and cyanidin-3-O-sambubiosides from Hibiscus sabdariffa. Journal of Ethnopharmacology, 127(1), 7–10. https://doi.org/10.1016/j.jep.2009.09.059

Patel, S., & Adhav, M. (2016). Comparative phytochemical screening of ethanolic extracts (flower and leaf) of morphotypes of Hibiscus Rosa-sinensis Linn. Journal of Pharmacognosy and Phytochemistry, 5(3), 93.

Pethe, M, & Guptha, P. (2011). Effect of Hibiscus Rosa Sinensis ( Jaswand) Flowers on Lipid Profile in Experimentally Induced Diabetes Mellitus in Rats. Faridpur Medical College Journal, 6(2), 70–73.

Pethe, Mohan, Yelwatkar, S., Manchalwar, S., & Gujar, V. (2017). Evaluation of Biological Effects of Hydroalcoholic Extract of Hibiscus Rosa Sinensis Flowers on Alloxan Induced Diabetes in Rats. Drug Research, 67(08), 485–492. https://doi.org/10.1055/s-0043-109434

Purushothaman, A., Meenatchi, P., S, S., Sundaram, R., & Saravanan, N. (2018). Quantification of Total Phenolic Content, HPLC Analysis of Flavonoids and Assessment of Antioxidant and Anti-haemolytic Activities of Hibiscus rosa-sinensis L. Flowers in vitro. International Journal of Pharma Research and Health Sciences, 4(5), 134–150. https://doi.org/10.21276/ijprhs.2016.05.02

Raduan, S. Z., Abdul Aziz, M. W. H., Roslida, A. H., Zakaria, Z. A., Zuraini, A., & Hakim, M. N. (2013). Anti- inflammatory effects of Hibiscus rosa-sinensis L. and Hibiscus rosa-sinensis var. alba ethanol extracts. International Journal of Pharmacy and Pharmaceutical Sciences.

Reagan-Shaw, S., Nihal, M., & Ahmad, N. (2008). Dose translation from animal to human studies revisited. The FASEB Journal, 22(3), 659–661. https://doi.org/10.1096/fj.07-9574LSF

Ross, I. A. (2003). Hibiscus rosa-sinensis. In Medicinal Plants of the World (pp. 253–266). Totowa, NJ: Humana Press. https://doi.org/10.1007/978-1-59259-365-1_12

Sachdewa, A., & Khemani, L. . (2003). Effect of Hibiscus rosa sinensis Linn. ethanol flower extract on blood glucose and lipid profile in streptozotocin induced diabetes in rats. Journal of Ethnopharmacology, 89(1), 61–66. https://doi.org/10.1016/S0378-8741(03)00230-7

Sharma, K., Pareek, A., & Chauhan, E. S. (2016). Evaluation of Hyperglycemic and Hyperlipidemic Mitigating Impact of Hibiscus Rosa Sinensis (Gudhal) Flower in Type Ii Diabetes Mellitus Subjects, 7(2), 223–229.

Silva, T. L., Afiune, L. A. F., de Moraes Souza, R. Q., de Sousa Soares, T., Carneiro, T. B., Américo, M. F., Volpato, G. T. (2015). Effect of Hibiscus rosa sinensis aqueous extract treatment on biochemical parameters in diabetic pregnant rats. Diabetology & Metabolic Syndrome, 7(S1), A77. https://doi.org/10.1186/1758-5996-7-S1-A77

SK, W., Lim, Y., & Chan, E. (2009). Antioxidant properties of hibiscus: Species variation, altitudinal change, coastal influence and floral colour change. Journal of Tropical Forest Science, 21(4), 307–315.

Subramanium, S., & Nair, A. (1972). Flavonoids of four Malvaceous plants. Phytochemistry, 11(4), 1518–1519.

Upadhyay, S. M., Upadhyay, P., Ghosh, A. K., Singh, V., & Dixit, V. K. (2011). Effect of ethanolic extract of Hibiscus rosa sinensis L., flowers on hair growth in female wistar rats. Der Pharmacia Lettre, 3(4), 258–263.

Venkatesh, S., Thilagavathi, J., & Shyam sundar, D. (2008). Anti-diabetic activity of flowers of Hibiscus rosasinensis. Fitoterapia. https://doi.org/10.1016/j.fitote.2007.06.015

Wealth of India. (1997). Raw Materials (Vol. VI). New Delhi.

DOI: https://doi.org/10.14421/biomedich.2021.101.59-65


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Copyright (c) 2021 Subhashinie Sanadheera, Deepanjana Subasinghe, Melissa Nethmi Solangaarachchi, Manju Suraweera, Noshara Yushanthi Suraweera, Nadeesha Tharangika

Biology, Medicine, & Natural Product Chemistry
ISSN 2089-6514 (paper) - ISSN 2540-9328 (online)
Published by Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity.

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