A Chemical Overview of Azanza garckeana

Yilni Edward Bioltif, Naanma Bioltif Edward, Terry Dalyop Tyeng


Azanza garckeana is a popular fruit tree in Nigeria, specifically in Gombe State, where it is locally called ‘goron tula’ which means ‘Kola of Tula’. It is also found in part of some African countries. Different plant part of this small tree/shrub has recorded different uses by the locals; uses ranging from its fruits being edible and others parts helping to remedy different diseases, especially sexually related diseases. It also records use as booster for sexual performance. The uses of the plant are majorly attributed to the presence of chemicals. Its local use initiates the necessity of this review to enhance the research for drug discovery since Chemicals are the chief constituencies responsible for its medicinal importance.


Azanza garckeana; Chemical; Compounds; Mansonone

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Dikko, Y. J., Khan, M. E., Tor-Anyiin, T. A., Anyam, J. V. and Linus, U. A. (2016). In vitro antimicrobial activity of fruit pulp extracts of Azanza garckeana (F. Hoffm.) Exell and Hillc. and isolation of one of its active principles, Betulinic acid. Br. J. Pharm. Res., 14: 1-10

Maroy, A. (2017). Azanza garckeana Fruit Tree: Phytochemistry, Pharmacology, Nutritional and Primary Healthcare Applications as Herbal Medicine: A Review. Res. J. Med. Plants, 11 (4): 115-123, 2017.

Musinguzi, E. L., Kikafunda, J. K. and Kiremire, B. T. (2007). Promoting indigenous wild edible fruits to complement roots and tuber crops in alleviating Vitamin A. deficiencies in Uganda. Proceedings of the 13th ISTRC Symposium.; 763-769.

Nkafamiya, I. I., Modibbo, U. U., Manji, A. J. and Haggai, D. (2007). Nutrient content of seeds of some wild plants. Afr. J. Biotech. 6(14):1665-1669.

Aberoumand, A. and Deokule, S. S. (2009). Studies on nutritional values of some wild edible plants from Iran and India. Pak. J. Nutrition. 8(1): 26-31.

Nazarudeen, A. (2010). Nutritional composition of some lesser-known fruits used by ethnic communities and local folks of Kerela. Ind. J. Traditional Knowl., 9(2): 398-402.

Food and agricultural organization (FAO) (1983). Food and fruit bearing forest species. Examples from Eastern Africa. Food and Agricultural Organization, Forestry Rome.14-16.

Nkafamiya, I. I., Ardo, B. P., Osemeahon S. A. and Akinterinwa, A. (2016). Evaluation of Nutritional, Non-nutritional, Elemental Content and Amino Acid Profile of Azanza garckeana (Goron Tula). British Journal of Applied Science & Technology, 12(6): 1-10.

Keshmiri-Neghab, H. and Goliaei, B. (2014). Therapeutic potential of gossypol: An overview. Pharmaceutical Biology, 52(1): 124–128. https://doi.org/10.3109/13880209.2013.832776

Mellon, J.E., Dowd, M.K., Beltz, S.B. and Moore, G.G. (2014). Growth inhibitory effects of gossypol and related compounds on fungal cotton root pathogens. Letters in Applied Microbiology 59, 161-168.

Ogbe, R. J., Ochalefu, D. O., Mafulul, S. G. and Olaniru, O. B. (2015). A review on dietary phytosterols: Their occurrence, metabolism and health benefits. Asian J. Plant Sci. Res., 5(4):10-21.

Mongkol1, R. and Chavasiri, W. (2016). Antimicrobial, herbicidal and antifeedant activities of mansonone E from the heartwoods of Mansonia gagei Drumm. Journal of Integrative Agriculture 15(12): 2795–2802.

Moghaddam, M. G. Ahmad, F. B. H. and Samzadeh-Kermani, A. (2012). Biological Activity of Betulinic Acid: A Review. Pharmacology & Pharmacy, 3, 119-123.

Mahalapbutr, P., Wonganan, P., Charoenwongpaiboon, T., Prousoontorn, M., Chavasiri, W. and T. Rungrotmongkol (2019). Enhanced Solubility and Anticancer Potential of Mansonone G by β-Cyclodextrin-Based Host-Guest Complexation: A Computational and Experimental Study, Biomolecules, 9: 1-17. doi:10.3390/biom9100545

Ivanescu, B., Vlase, L. and A. Corciova (2013). Importance of phytosterols and their determination in herbal medicines, The 4th IEEE International Conference on E-Health and Bioengineering,

Ochokwu, I. J., Dasuki, A., & Oshoke, J. O. (2015). Azanza garckeana (Goron Tula) as an edible indigenous fruit in North Eastern Part of Nigeria. Journal of Biology, Agericulture and Healthcare, 5(15), 26-31.

DOI: https://doi.org/10.14421/biomedich.2020.92.91-95


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Copyright (c) 2020 Yilni Edward Bioltif, Naanma Bioltif Edward, Terry Dalyop Tyeng

Biology, Medicine, & Natural Product Chemistry

ISSN 2089-6514 (paper) - ISSN 2540-9328 (online)
Sunan Kalijaga State Islamic University &
Society for Indonesian Biodiversity

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